吴旭 （WU, Xu）

博士，副研究员，硕士研究生导师。

邮箱：wuxulz@126.com

办公室地址：四川省泸州市龙马潭区商贸城17区B座3层5街川南医学转化研究院

     现为西南医科大学副教授、硕士研究生导师。先后于中国中医科学院中药研究所、香港中文大学医学院获得硕士、博士学位。四川省海外高层次留学人才。研究方向为中药（民族药）药效评价及应用研究。发表SCI论文100余篇，H指数29。迄今主持科研项目16项，包括国家自然科学基金项目2项、省部级3项。入选2020-2022西南医科大学青年科技特别支持计划。申请国家发明专利3项，授权2项。学术兼职：四川省药理学会理事、四川省药理学会肿瘤药理专委会委员、世中联学会网络药理学专委会常务理事、Journal of pharmaceutical analysis杂志青年编委、Chinese Herbal Medicines杂志青年编委、Frontiers in oncology及Evidence-based complementary and alternative medicine等杂志编委。

       代表性论文：

1. Hongxun Tao, Xu Wu, Jiliang Cao, Yu Peng, Anqi Wang, Jin Pei, Jianbo Xiao, Shengpeng Wang*, Yitao Wang*, Rhodiola species: A comprehensive review of traditional use, phytochemistry, pharmacology, toxicity, and clinical study. Medicinal Research Review. 2019, 39(5):1779-1850.

2. Yang Y, Li M, Liu Q, Zhao Q, Zeng J, Wang Q, Zhao Y, Du F, Chen Y, Shen J, Luo H, Wang S, Li W, Chen M, Li X, Wang F, Sun Y, Gu L, Xiao Z, Du Y*, Wu X*. Starch from Pueraria lobata and the amylose fraction alleviates dextran sodium sulfate induced colitis in mice. Carbohydr Polym. 2023; 302: 120329.

3. Zeng J, Li M, Zhao Q, Chen M, Zhao L, Wei S, Yang H, Zhao Y, Wang A, Shen J, Du F, Chen Y, Deng S, Wang F, Zhang Z, Li Z, Wang T, Wang S, Xiao Z*, Wu X*. Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases, J Pharm Anal. 2023; 13(6): 545-562.

4. Haoming Luo, Mingxing Li, Fang Wang, Yifei Yang, Qin Wang, Yueshui Zhao, Fukuan Du, Yu Chen, Jing Shen, Qianyun Zhao, Jiuping Zeng, Shengpeng Wang, Meijuan Chen, Xiaobing Li, Wanping Li, Yuhong Sun, Li Gu, Qinglian Wen, Zhangang Xiao*, Xu Wu*. The role of intestinal stem cell within gut homeostasis: Focusing on its interplay with gut microbiota and the regulating pathways. International Journal of Biological Sciences. 2022; 18(13):5185-5206.

5. Li H, Wang Y, Shao S, Yu H, Wang D, Li C, Yuan Q, Liu W, Cao J, Wang X, Guo H, Wu X*, Wang S.*, Rabdosia serra alleviates dextran sulfate sodium salt-induced colitis in mice through anti-inflammation, regulating Th17/Treg balance, maintaining intestinal barrier integrity, and modulating gut microbiota. J Pharm Anal. 2022; 12(6): 824-838.

6. Yifei Yang; …; Xu Wu*. Pueraria lobata starch regulates gut microbiota and alleviates high-fat high-cholesterol diet induced non-alcoholic fatty liver disease in mice. Food Research International. 2022, 157, 111401.

7. Shiyun Chen, Zhejie Chen, Yi Wang, Wei Hao, Qin Yuan, Hefeng Zhou, Caifang Gao, Yitao Wang, Xu Wu*, Shengpeng Wang*. Targeted delivery of Chinese herb pair-based berberine/tannin acid self-assemblies for the treatment of ulcerative colitis. Journal of Advanced Research. 2022, 40, 263-276.

8. Wu, Xu; Yin, Chun; Ma, Jiang; Chai, Stella; Zhang, Chunyuan; Yao, Sheng; Kadioglu, Onat; Efferth, Thomas; Ye, Yang; To, Kenneth Kin-Wah*; Lin, Ge*. Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo. Acta Pharm Sin B. 2021; 11(7): 1885-1902.

9. Xu Wu^#, Jiliang Cao^#, Mingxing Li, Peifen Yao, Hongyi Li, Wendong Xu, Cheng Yuan, Juyan Liu, Shengpeng Wang*, Peng Li*, Yitao Wang. An integrated microbiome and metabolomic analysis identifies immunoenhancing features of Ganoderma lucidum spores oil in mice. Pharmacological Research, 2020, 138: 104937.

10. Xu Wu^#, Mingxing Li^#, Zhangang Xiao^#, Maria Daglia, Simona Dragan, Dominique Delmas, Chi Teng Vong, Yitao Wang, Yueshui Zhao, Jing Shen, Seyed Mohammad Nabavi, Antoni Sureda, Hui Cao, Mingfu Wang, Chongde Sun, Shengpeng Wang*, Jianbo Xiao*, Dietary polyphenols for managing cancers: What have we ignored? Trends in Food Science & Technology, 2020, 101: 150-164.

11. Xiaoxiao Wu; Shengpeng Wang; Mingxing Li; Jing Li; Jing Shen; Yueshui Zhao; Jun Pang; Qinglian Wen; Meijuan Chen; Bin Wei; Parham Jabbarzadeh Kaboli; Fukuan Du; Qijie Zhao; Chi Hin Cho; Yitao Wang; Zhangang Xiao*; Xu Wu*; Conditional reprogramming: next generation cell culture, Acta Pharmaceutica Sinica B, 2020, 10(8): 1360-1381.